Are race-specific ERCC1 haplotypes in melanoma cases versus controls related to the predictive and prognostic value of ERCC1 N118N?

OBJECTIVES: Although it does not alter the ERCC1 phenotype, the ERCC1 500C>T (rs11615) polymorphism has undergone a myriad of investigations into its role as a marker for nucleotide excision repair (NER) function in different races, diseases and treatment outcomes. The goal of our study was to te...

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Detalhes bibliográficos
Main Authors: Gao, Rui, Reece, Kelie M, Sissung, Tristan, Fu, Samuel H, Venzon, David J, Reed, Eddie, Spencer, Shawn D, Price, Douglas K, Figg, William D
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2013
Assuntos:
Dermatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549215/
https://ncbi.nlm.nih.gov/pubmed/23293248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2012-002030
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