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Effect of SLCO1B3 haplotype on testosterone transport and clinical outcome in Caucasian patients with androgen-independent prostatic cancer

PURPOSE: The organic anion transporter OATP1B3, encoded by SLCO1B3, is involved in the transport of steroid hormones. However, its role in testosterone uptake and clinical outcome of prostatic cancer is unknown. This study examined: 1) the SLCO1B3 genotype in cancer cells as well as the uptake of te...

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Detalhes bibliográficos
Main Authors: Hamada, Akinobu, Sissung, Tristan, Price, Douglas K., Danesi, Romano, Chau, Cindy H., Sharifi, Nima, Venzon, David, Maeda, Kenji, Nagao, Keisuke, Sparreboom, Alex, Mitsuya, Hiroaki, Dahut, William L., Figg, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701141/
https://ncbi.nlm.nih.gov/pubmed/18519758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4118
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