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The genetics of castrate-resistant prostate cancer: What can the germline tell us?

Androgen deprivation therapy (ADT) is the cornerstone treatment for advanced prostate cancer. Despite frequent responses, the majority of metastatic tumors will progress to castrate-resistant prostate cancer (CRPC). Numerous molecular and genetic perturbations have been described in CRPC, which are...

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Detalhes bibliográficos
Main Authors: Sharifi, Nima, Dahut, William L., Figg, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698703/
https://ncbi.nlm.nih.gov/pubmed/18676736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0453
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