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The ERCC1 N118N polymorphism does not change cellular ERCC1 protein expression or platinum sensitivity
Genetic polymorphisms in ERCC1 are thought to contribute to altered sensitivity to platinum-based chemotherapy. Although ERCC1 N118N (500 C>T, rs11615) is the most studied polymorphism, the impact of this polymorphism on platinum-based chemotherapy remains unclear. This is the first study in whic...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057957/ https://ncbi.nlm.nih.gov/pubmed/21315089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.01.002 |
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