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Structural basis for cooperativity of CRM1 export complex formation

In eukaryotes, the nucleocytoplasmic transport of macromolecules is mainly mediated by soluble nuclear transport receptors of the karyopherin-β superfamily termed importins and exportins. The highly versatile exportin chromosome region maintenance 1 (CRM1) is essential for nuclear depletion of numer...

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Autors principals: Monecke, Thomas, Haselbach, David, Voß, Béla, Russek, Andreas, Neumann, Piotr, Thomson, Emma, Hurt, Ed, Zachariae, Ulrich, Stark, Holger, Grubmüller, Helmut, Dickmanns, Achim, Ficner, Ralf
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549083/
https://ncbi.nlm.nih.gov/pubmed/23277578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215214110
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