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Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity
The oncogenic transcription factor c-Myc causes transformation and tumorigenesis, but it can also induce apoptotic cell death. Although tumor suppressors are necessary for c-Myc to induce apoptosis, the pathways and mechanisms are unclear. To further understand how c-Myc switches from an oncogenic p...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549076/ https://ncbi.nlm.nih.gov/pubmed/23277542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208334110 |
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