Cellular toxicity of mutant SOD1 protein is linked to an easily soluble, non-aggregated form in vitro

Lignende værker

• Susceptibility of Mutant SOD1 to Form a Destabilized Monomer Predicts Cellular Aggregation and Toxicity but Not In vitro Aggregation Propensity
  af: McAlary, Luke, et al.
  Udgivet: (2016)
• Single chain variable fragment antibodies block aggregation and toxicity induced by familial ALS-linked mutant forms of SOD1
  af: Ghadge, Ghanashyam D., et al.
  Udgivet: (2013)
• Huntingtin Fragments and SOD1 Mutants Form Soluble Oligomers in the Cell
  af: Park, Yang-Nim, et al.
  Udgivet: (2012)
• An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1
  af: Prudencio, Mercedes, et al.
  Udgivet: (2010)
• Dysregulation of the proteasome increases the toxicity of ALS-linked mutant SOD1
  af: Kitamura, Akira, et al.
  Udgivet: (2014)