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Evolving concepts on regulation and function of renin in distal nephron
Sustained stimulation of the intrarenal/intratubular renin–angiotensin system in a setting of elevated arterial pressure elicits renal vasoconstriction, increased sodium reabsorption, proliferation, fibrosis, and eventual renal injury. Activation of luminal AT(1) receptors in proximal and distal nep...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549013/ https://ncbi.nlm.nih.gov/pubmed/22990760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-012-1151-6 |
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