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DNA damage-specific control of cell death by cryptochrome in p53 mutant Ras-transformed cells
The main feedback loop driving circadian rhythm in mice is controlled in part by the genes encoding the cryptochromes Cry1 and Cry2. Targeted mutation of both Cry1 and Cry2 delay the early onset of tumor formation in p53 null mutant mice. Furthermore, Ras-transformed p53 and Cry null mouse skin fibr...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548992/ https://ncbi.nlm.nih.gov/pubmed/23149912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1994 |
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