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Loss of cryptochrome reduces cancer risk in p53 mutant mice

It is commonly thought that disruption of the circadian clock increases the cancer incidence in humans and mice. However, it was found that disruption of the clock by the Cryptochrome (Cry) mutation in mice did not increase cancer rate in the mutant mice even after exposing the animals to ionizing r...

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Detalhes bibliográficos
Main Authors: Ozturk, Nuri, Lee, Jin Hyup, Gaddameedhi, Shobhan, Sancar, Aziz
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634797/
https://ncbi.nlm.nih.gov/pubmed/19188586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813028106
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