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Loss of cryptochrome reduces cancer risk in p53 mutant mice

It is commonly thought that disruption of the circadian clock increases the cancer incidence in humans and mice. However, it was found that disruption of the clock by the Cryptochrome (Cry) mutation in mice did not increase cancer rate in the mutant mice even after exposing the animals to ionizing r...

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Autores principales: Ozturk, Nuri, Lee, Jin Hyup, Gaddameedhi, Shobhan, Sancar, Aziz
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634797/
https://ncbi.nlm.nih.gov/pubmed/19188586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813028106
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