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Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
The circadian clock in mammalian organisms is generated by a transcription–translation feedback loop that controls many biochemical pathways at the cellular level and physiology and behavior at the organismal level. Cryptochrome (Cry) is a key protein in the negative arm of the transcription–transla...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127903/ https://ncbi.nlm.nih.gov/pubmed/21628572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106284108 |
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