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Discrimination between CO and O(2) in heme oxygenase: Comparison of static structures and dynamic conformation changes following CO photolysis
Heme oxygenase (HO) catalyzes heme degradation, one of whose products is carbon monoxide (CO). It is well known that CO has a higher affinity for heme iron than does molecular oxygen (O(2)), therefore CO is potentially toxic. Because O(2) is required for the HO reaction, HO must discriminate effecti...
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| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548955/ https://ncbi.nlm.nih.gov/pubmed/23043644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301175x |
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