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Alternative cyanide-binding modes to the haem iron in haem oxygenase
Cyanide is a well known potent inhibitor of haem proteins, including haem oxygenase (HO). Generally, cyanide coordinates to the ferric haem iron with a linear binding geometry; the Fe—C—N angle ranges from 160 to 180°. The Fe—C—N angle observed in the crystal structure of haem–HO bound to cyanide p...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2335079/ https://ncbi.nlm.nih.gov/pubmed/17554165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910702475X |
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