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Evidence for the putative cannabinoid receptor, GPR55, mediated inhibitory effects on intestinal contractility in mice
BACKGROUND: Cannabinoids inhibit intestinal motility via presynaptic cannabinoid receptor type I(CB1) in enteric neurons while cannabinoid receptor type II (CB2) receptors are located mainly in immune cells. The recently deorphanized G-protein-coupled receptor, GPR55, has been proposed to be the “th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548934/ https://ncbi.nlm.nih.gov/pubmed/22759743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000339076 |
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