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The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

GPR55 is a G protein-coupled receptor recently shown to be activated by certain cannabinoids and by lysophosphatidylinositol (LPI). However, the physiological role of GPR55 remains unknown. Given the recent finding that the cannabinoid receptors CB(1) and CB(2) affect bone metabolism, we examined th...

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Hlavní autoři: Whyte, Lauren S., Ryberg, Erik, Sims, Natalie A., Ridge, Susan A., Mackie, Ken, Greasley, Peter J., Ross, Ruth A., Rogers, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737440/
https://ncbi.nlm.nih.gov/pubmed/19805329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902743106
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