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Evidence for the putative cannabinoid receptor, GPR55, mediated inhibitory effects on intestinal contractility in mice

BACKGROUND: Cannabinoids inhibit intestinal motility via presynaptic cannabinoid receptor type I(CB1) in enteric neurons while cannabinoid receptor type II (CB2) receptors are located mainly in immune cells. The recently deorphanized G-protein-coupled receptor, GPR55, has been proposed to be the “th...

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Detalhes bibliográficos
Main Authors: Ross, Gracious R, Lichtman, Aron, Dewey, William L, Akbarali, Hamid I
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548934/
https://ncbi.nlm.nih.gov/pubmed/22759743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000339076
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