Evaluation of Histone Deacetylase Inhibitors as Therapeutics for Neurodegenerative Diseases

Various neurodegenerative diseases are associated with aberrant gene expression. We recently identified a novel class of pimelic o-aminobenzamide histone deacetylase (HDAC) inhibitors that show promise as therapeutics in the neurodegenerative diseases Friedreich’s ataxia (FRDA) and Huntington’s dise...

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Hlavní autoři: Soragni, Elisabetta, Xu, Chunping, Cooper, Andrew, Plasterer, Heather L., Rusche, James R., Gottesfeld, Joel M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548622/
https://ncbi.nlm.nih.gov/pubmed/21913121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-328-8_32
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