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Development of histone deacetylase inhibitors as therapeutics for neurological disease
Postsynthetic modifications of histone and other chromosomal proteins by reversible acetylation and/or methylation regulate many aspects of chromatin dynamics, such as transcription, replication and DNA repair. Aberrant modification states are associated with several neurological and neuromotor dise...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824892/ https://ncbi.nlm.nih.gov/pubmed/20177429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl.09.55 |
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