Proinsulin Intermolecular Interactions during Secretory Trafficking in Pancreatic β Cells

Classically, exit from the endoplasmic reticulum (ER) is rate-limiting for secretory protein trafficking because protein folding/assembly occurs there. In this study, we have exploited “hPro-CpepSfGFP,” a human proinsulin bearing “superfolder” green fluorescent C-peptide expressed in pancreatic β ce...

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Hlavní autoři: Haataja, Leena, Snapp, Erik, Wright, Jordan, Liu, Ming, Hardy, Alexandre B., Wheeler, Michael B., Markwardt, Michele L., Rizzo, Mark, Arvan, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548498/
https://ncbi.nlm.nih.gov/pubmed/23223446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420018
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