Regulation of Xylosyltransferase I Gene Expression by Interleukin 1β in Human Primary Chondrocyte Cells: MECHANISM AND IMPACT ON PROTEOGLYCAN SYNTHESIS

Xylosyltransferase I (XT-I) is an essential enzyme of proteoglycan (PG) biosynthesis pathway catalyzing the initial and rate-limiting step in glycosaminoglycan chain assembly. It plays a critical role in the regulation of PG synthesis in cartilage; however, little is known about underlying mechanism...

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Bibliographic Details
Main Authors: Khair, Mostafa, Bourhim, Mustapha, Barré, Lydia, Li, Dong, Netter, Patrick, Magdalou, Jacques, Fournel-Gigleux, Sylvie, Ouzzine, Mohamed
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548487/
https://ncbi.nlm.nih.gov/pubmed/23223231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419887
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