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CFTR Modulation by the Tobacco Smoke Toxin Acrolein

OBJECTIVES: Evidence indicates that decreased mucociliary clearance (MCC) is a major contributing feature to chronic rhinosinusitis. Tobacco-smoke exposure is thought to inhibit transepithelial Cl(−) secretion – a major determinant of airway surface liquid hydration and MCC. The objective of the cur...

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Bibliografische gegevens
Hoofdauteurs: Alexander, Nathan S., Blount, Angela, Zhang, Shaoyan, Skinner, Daniel, Hicks, Stephen B., Chestnut, Michael, Kebbel, Frederick A., Sorscher, Eric J., Woodworth, Bradford A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548450/
https://ncbi.nlm.nih.gov/pubmed/22522920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.23278
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