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Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

The opportunistic human pathogenic fungus Aspergillus fumigatus produces at least two types of melanin, namely pyomelanin and dihydroxynaphthalene (DHN) melanin. Pyomelanin is produced during tyrosine catabolism via accumulation of homogentisic acid. Although pyomelanin protects the fungus against r...

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Bibliographische Detailangaben
Hauptverfasser: Heinekamp, Thorsten, Thywißen, Andreas, Macheleidt, Juliane, Keller, Sophia, Valiante, Vito, Brakhage, Axel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548413/
https://ncbi.nlm.nih.gov/pubmed/23346079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2012.00440
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