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Notch Suppresses Nuclear Factor of Activated T Cells (Nfat) Transactivation and Nfatc1 Expression in Chondrocytes

Notch1 to Notch4 transmembrane receptors determine cell fate, and release of the Notch intracellular domain (NICD) in the cytoplasm induces gene expression. Notch regulates endochondral ossification, but it is not clear whether Notch interacts with signals controlling chondrocyte differentiation. Nu...

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Detalhes bibliográficos
Main Authors: Zanotti, Stefano, Canalis, Ernesto
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548184/
https://ncbi.nlm.nih.gov/pubmed/23264614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1925
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