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Interleukin 6 Mediates Select Effects of Notch in Chondrocytes

OBJECTIVE: Notch receptors determine cell fate by regulating transcription, an event mediated by the Notch intracellular domain (NICD), which is generated by proteolysis brought about by Notch-ligand interactions. Since Notch activation or exposure to interleukin (Il)6 have similar effects in chondr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zanotti, Stefano, Canalis, Ernesto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795792/
https://ncbi.nlm.nih.gov/pubmed/23954701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2013.08.010
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