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CONNECTIVE TISSUE GROWTH FACTOR (CTGF) TRANSACTIVATES NUCLEAR FACTOR OF ACTIVATED T CELLS (NFAT) IN CELLS OF THE OSTEOBLASTIC LINEAGE

Connective Tissue Growth Factor (CTGF), a member of the Cyr 61, CTGF, Nov (CCN) family of proteins, regulates multiple cellular functions. Overexpression of CTGF in vivo causes osteopenia, but in vitro CTGF can induce osteoblastogenesis. To investigate mechanisms involved in the effects of CTGF on o...

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Autori principali: Smerdel-Ramoya, Anna, Zanotti, Stefano, Canalis, Ernesto
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008370/
https://ncbi.nlm.nih.gov/pubmed/20235153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22561
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