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Mutant of herpes simplex virus type 1 conditionally able to transform thymidine kinaseless L cells to a tk+ phenotype.

After nitrous acid mutagenesis of herpes simplex virus type 1 (HSV-1), a mutant, 1093, was isolated which, during productive infection, induced very low levels of thymidine kinase (tk). The mutant virus was found, after UV irradiation, to be unable to transform L cells lacking tk (Ltk-) to a tk+ phe...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Hughes, R G, Munyon, W H
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1976
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC354785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/178926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.18.3.867-872.1976
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