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Mutant of herpes simplex virus type 1 conditionally able to transform thymidine kinaseless L cells to a tk+ phenotype.

After nitrous acid mutagenesis of herpes simplex virus type 1 (HSV-1), a mutant, 1093, was isolated which, during productive infection, induced very low levels of thymidine kinase (tk). The mutant virus was found, after UV irradiation, to be unable to transform L cells lacking tk (Ltk-) to a tk+ phe...

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Detalles Bibliográficos
Autores principales: Hughes, R G, Munyon, W H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1976
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC354785/
https://ncbi.nlm.nih.gov/pubmed/178926
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