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Properties of Cells Carrying the Herpes Simplex Virus Type 2 Thymidine Kinase Gene: Mechanisms of Reversion to a Thymidine Kinase-Negative Phenotype

We have isolated cells with a thymidine kinase-negative (tk(−)) phenotype from cells which carry the herpes simplex virus type 2 tk gene by selection in 5-bromodeoxyuridine or 9-(2-hydroxyethoxymethyl)guanine. Both selection routines generated revertants with a frequency of 10(−3) to 10(−4), and res...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Bastow, K. F., Darby, G., Wildy, P., Minson, A. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353702/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16789205/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.36.3.746-755.1980
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