Inhibition of Herpes Simplex Virus Type 2 Replication by Thymidine

Replication of herpes simplex virus type 2 (HSV-2) was impeded in KB cells which were blocked in their capacity to synthesize DNA by 2 mM thymidine (TdR). The degree of inhibition was dependent upon the concentration of TdR. In marked contrast, HSV-1 is able to replicate under these conditions. The...

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Bibliographic Details
Published in:J Virol
Main Authors: Cohen, Gary H., Factor, Mindie N., de Leon, Manuel Ponce
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1974
Subjects:
Animal Viruses
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC355472/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4365718/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.14.1.20-25.1974
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