Integrative Genomics in Combination with RNA Interference Identifies Prognostic and Functionally Relevant Gene Targets for Oral Squamous Cell Carcinoma

In oral squamous cell carcinoma (OSCC), metastasis to lymph nodes is associated with a 50% reduction in 5-year survival. To identify a metastatic gene set based on DNA copy number abnormalities (CNAs) of differentially expressed genes, we compared DNA and RNA of OSCC cells laser-microdissected from...

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Detalhes bibliográficos
Main Authors: Xu, Chang, Wang, Pei, Liu, Yan, Zhang, Yuzheng, Fan, Wenhong, Upton, Melissa P., Lohavanichbutr, Pawadee, Houck, John R., Doody, David R., Futran, Neal D., Zhao, Lue Ping, Schwartz, Stephen M., Chen, Chu, Méndez, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547824/
https://ncbi.nlm.nih.gov/pubmed/23341773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003169
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