Integrative Genomics in Combination with RNA Interference Identifies Prognostic and Functionally Relevant Gene Targets for Oral Squamous Cell Carcinoma

In oral squamous cell carcinoma (OSCC), metastasis to lymph nodes is associated with a 50% reduction in 5-year survival. To identify a metastatic gene set based on DNA copy number abnormalities (CNAs) of differentially expressed genes, we compared DNA and RNA of OSCC cells laser-microdissected from...

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Библиографические подробности
Главные авторы: Xu, Chang, Wang, Pei, Liu, Yan, Zhang, Yuzheng, Fan, Wenhong, Upton, Melissa P., Lohavanichbutr, Pawadee, Houck, John R., Doody, David R., Futran, Neal D., Zhao, Lue Ping, Schwartz, Stephen M., Chen, Chu, Méndez, Eduardo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547824/
https://ncbi.nlm.nih.gov/pubmed/23341773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003169
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