Integrative Genomics in Combination with RNA Interference Identifies Prognostic and Functionally Relevant Gene Targets for Oral Squamous Cell Carcinoma

In oral squamous cell carcinoma (OSCC), metastasis to lymph nodes is associated with a 50% reduction in 5-year survival. To identify a metastatic gene set based on DNA copy number abnormalities (CNAs) of differentially expressed genes, we compared DNA and RNA of OSCC cells laser-microdissected from...

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Bibliographic Details
Main Authors: Xu, Chang, Wang, Pei, Liu, Yan, Zhang, Yuzheng, Fan, Wenhong, Upton, Melissa P., Lohavanichbutr, Pawadee, Houck, John R., Doody, David R., Futran, Neal D., Zhao, Lue Ping, Schwartz, Stephen M., Chen, Chu, Méndez, Eduardo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547824/
https://ncbi.nlm.nih.gov/pubmed/23341773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003169
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