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Evolutionary Optimization of Protein Folding

Nature has shaped the make up of proteins since their appearance, [Image: see text]3.8 billion years ago. However, the fundamental drivers of structural change responsible for the extraordinary diversity of proteins have yet to be elucidated. Here we explore if protein evolution affects folding spee...

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Detalhes bibliográficos
Main Authors: Debès, Cédric, Wang, Minglei, Caetano-Anollés, Gustavo, Gräter, Frauke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547816/
https://ncbi.nlm.nih.gov/pubmed/23341762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002861
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