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Structural Phylogenomics Reveals Gradual Evolutionary Replacement of Abiotic Chemistries by Protein Enzymes in Purine Metabolism

The origin of metabolism has been linked to abiotic chemistries that existed in our planet at the beginning of life. While plausible chemical pathways have been proposed, including the synthesis of nucleobases, ribose and ribonucleotides, the cooption of these reactions by modern enzymes remains shr...

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מידע ביבליוגרפי
Main Authors: Caetano-Anollés, Kelsey, Caetano-Anollés, Gustavo
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596326/
https://ncbi.nlm.nih.gov/pubmed/23516625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059300
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