Anti-thymocyte globulin (ATG) differentially depletes naïve and memory T cells and permits memory-type regulatory T cells in nonobese diabetic mice

BACKGROUND: ATG has been employed to deplete T cells in several immune-mediated conditions. However, whether ATG administration affects naïve and memory T cell differently is largely unknown. THE CONTEXT AND PURPOSE OF THE STUDY: In this study, we assessed how murine ATG therapy affected T cell subs...

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Autores principales: Xia, Chang-Qing, Chernatynskaya, Anna V, Wasserfall, Clive H, Wan, Suigui, Looney, Benjamin M, Eisenbeis, Scott, Williams, John, Clare-Salzler, Michael J, Atkinson, Mark A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547787/
https://ncbi.nlm.nih.gov/pubmed/23237483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-13-70
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