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Immune Depletion With Cellular Mobilization Imparts Immunoregulation and Reverses Autoimmune Diabetes in Nonobese Diabetic Mice

OBJECTIVE: The autoimmune destruction of β-cells in type 1 diabetes results in a loss of insulin production and glucose homeostasis. As such, an immense interest exists for the development of therapies capable of attenuating this destructive process through restoration of proper immune recognition....

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Detalhes bibliográficos
Main Authors: Parker, Matthew J., Xue, Song, Alexander, John J., Wasserfall, Clive H., Campbell-Thompson, Martha L., Battaglia, Manuela, Gregori, Silvia, Mathews, Clayton E., Song, Sihong, Troutt, Misty, Eisenbeis, Scott, Williams, John, Schatz, Desmond A., Haller, Michael J., Atkinson, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750219/
https://ncbi.nlm.nih.gov/pubmed/19628781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0557
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