Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis

The daily rhythm in melatonin levels is controlled by cAMP through actions on the penultimate enzyme in melatonin synthesis, arylalkylamine N-acetyltransferase (AANAT; serotonin N-acetyltransferase, EC 2.3.1.87). Results presented here describe a regulatory/binding sequence in AANAT that encodes a c...

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Bibliografiske detaljer
Main Authors: Ganguly, Surajit, Gastel, Jonathan A., Weller, Joan L., Schwartz, Christian, Jaffe, Howard, Namboodiri, M. A. A., Coon, Steven L., Hickman, Alison B., Rollag, Mark, Obsil, Tomas, Beauverger, Philippe, Ferry, Gilles, Boutin, Jean A., Klein, David C.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC35471/
https://ncbi.nlm.nih.gov/pubmed/11427721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141118798
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