Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis

The daily rhythm in melatonin levels is controlled by cAMP through actions on the penultimate enzyme in melatonin synthesis, arylalkylamine N-acetyltransferase (AANAT; serotonin N-acetyltransferase, EC 2.3.1.87). Results presented here describe a regulatory/binding sequence in AANAT that encodes a c...

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Detalhes bibliográficos
Main Authors: Ganguly, Surajit, Gastel, Jonathan A., Weller, Joan L., Schwartz, Christian, Jaffe, Howard, Namboodiri, M. A. A., Coon, Steven L., Hickman, Alison B., Rollag, Mark, Obsil, Tomas, Beauverger, Philippe, Ferry, Gilles, Boutin, Jean A., Klein, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC35471/
https://ncbi.nlm.nih.gov/pubmed/11427721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141118798
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