Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis

The daily rhythm in melatonin levels is controlled by cAMP through actions on the penultimate enzyme in melatonin synthesis, arylalkylamine N-acetyltransferase (AANAT; serotonin N-acetyltransferase, EC 2.3.1.87). Results presented here describe a regulatory/binding sequence in AANAT that encodes a c...

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Detalles Bibliográficos
Autores principales: Ganguly, Surajit, Gastel, Jonathan A., Weller, Joan L., Schwartz, Christian, Jaffe, Howard, Namboodiri, M. A. A., Coon, Steven L., Hickman, Alison B., Rollag, Mark, Obsil, Tomas, Beauverger, Philippe, Ferry, Gilles, Boutin, Jean A., Klein, David C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC35471/
https://ncbi.nlm.nih.gov/pubmed/11427721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141118798
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