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Regulation of Cytotoxic T Lymphocyte Antigen 4 by Cyclic AMP

Recent studies indicate that cyclic AMP (cAMP) induces cytotoxic T lymphocyte antigen (CTLA) 4. CTLA4 is expressed in T cells, and is a negative regulator of T cell activation. CTLA4 expression is regulated by T cell receptor plus CD28 (adaptive immune signaling) at both the transcriptional and post...

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Hlavní autoři: Li, Jinghong, Lin, Ko-Wei, Murray, Fiona, Nakajima, Takeshi, Zhao, Yandong, Perkins, David L., Finn, Patricia W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547085/
https://ncbi.nlm.nih.gov/pubmed/23024062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0155OC
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