In Vivo Targeting of ADAM9 Gene Expression Using Lentivirus-Delivered shRNA Suppresses Prostate Cancer Growth by Regulating REG4 Dependent Cell Cycle Progression

Cancer cells respond to stress by activating a variety of survival signaling pathways. A disintegrin and metalloproteinase (ADAM) 9 is upregulated during cancer progression and hormone therapy, functioning in part through an increase in reactive oxygen species. Here, we present in vitro and in vivo...

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Detalhes bibliográficos
Main Authors: Liu, Che-Ming, Hsieh, Chia-Ling, He, Yun-Chi, Lo, Sen-Jei, Liang, Ji-An, Hsieh, Teng-Fu, Josson, Sajni, Chung, Leland W. K., Hung, Mien-Chie, Sung, Shian-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547060/
https://ncbi.nlm.nih.gov/pubmed/23342005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053795
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