Activation of p53 by Chemotherapeutic Agents Enhances Reovirus Oncolysis

Mammalian reovirus is a benign virus that possesses the natural ability to preferentially infect and kill cancer cells (reovirus oncolysis). Reovirus exploits aberrant Ras signalling in many human cancers to promote its own replication and spread. In vitro and in vivo studies using reovirus either s...

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Detaylı Bibliyografya
Asıl Yazarlar: Pan, Da, Marcato, Paola, Ahn, Dae-Gyun, Gujar, Shashi, Pan, Lu-Zhe, Shmulevitz, Maya, Lee, Patrick W. K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546971/
https://ncbi.nlm.nih.gov/pubmed/23342061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054006
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