Activation of p53 by Chemotherapeutic Agents Enhances Reovirus Oncolysis

Mammalian reovirus is a benign virus that possesses the natural ability to preferentially infect and kill cancer cells (reovirus oncolysis). Reovirus exploits aberrant Ras signalling in many human cancers to promote its own replication and spread. In vitro and in vivo studies using reovirus either s...

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Bibliografiske detaljer
Main Authors: Pan, Da, Marcato, Paola, Ahn, Dae-Gyun, Gujar, Shashi, Pan, Lu-Zhe, Shmulevitz, Maya, Lee, Patrick W. K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546971/
https://ncbi.nlm.nih.gov/pubmed/23342061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054006
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