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Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition

Catechol-O-methyltransferase (COMT) catabolises the catecholamine neurotransmitters and influences cognitive function. COMT modulates dopamine levels in the prefrontal cortex and its action in this region is generally invoked to explain its effects on cognition. However, its role in other brain regi...

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Hlavní autoři: Laatikainen, LM, Sharp, T, Bannerman, DM, Harrison, PJ, Tunbridge, EM
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546629/
https://ncbi.nlm.nih.gov/pubmed/22815336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881112454228
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