Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition

Catechol-O-methyltransferase (COMT) catabolises the catecholamine neurotransmitters and influences cognitive function. COMT modulates dopamine levels in the prefrontal cortex and its action in this region is generally invoked to explain its effects on cognition. However, its role in other brain regi...

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Detalles Bibliográficos
Autores principales: Laatikainen, LM, Sharp, T, Bannerman, DM, Harrison, PJ, Tunbridge, EM
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2012
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Original Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546629/
https://ncbi.nlm.nih.gov/pubmed/22815336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881112454228
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