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Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition

Catechol-O-methyltransferase (COMT) catabolises the catecholamine neurotransmitters and influences cognitive function. COMT modulates dopamine levels in the prefrontal cortex and its action in this region is generally invoked to explain its effects on cognition. However, its role in other brain regi...

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Bibliografiske detaljer
Main Authors: Laatikainen, LM, Sharp, T, Bannerman, DM, Harrison, PJ, Tunbridge, EM
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546629/
https://ncbi.nlm.nih.gov/pubmed/22815336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881112454228
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