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Comparative analysis of virus-host interactomes with a mammalian high- throughput protein complementation assay based on Gaussia princeps luciferase

Comparative interactomics is a strategy for inferring potential interactions among orthologous proteins or “iginterologs”. Herein we focus, in contrast to standard homology-based inference, on the divergence of protein interaction profiles among closely related organisms, showing that the approach c...

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Huvudupphovsmän: Neveu, Grégory, Cassonnet, Patricia, Vidalain, Pierre-Olivier, Rolloy, Caroline, Mendoza, José, Jones, Louis, Tangy, Frédéric, Muller, Mandy, Demeret, Caroline, Tafforeau, Lionel, Lotteau, Vincent, Rabourdin-Combe, Chantal, Travé, Gilles, Dricot, Amélie, Hill, David E., Vidal, Marc, Favre, Michel, Jacob, Yves
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546263/
https://ncbi.nlm.nih.gov/pubmed/22898364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2012.07.029
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