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Sensitive in vivo imaging of T cells utilizing a membrane bound Gaussia princeps luciferase enzyme
We developed a novel approach to bioluminescent T cell imaging (BLI) using a membrane-anchored form of the Gaussia luciferase (GLuc) enzyme, termed extGLuc, which we could stably express in both mouse and human primary T cells. In vitro, extGLuc(+) cells emitted significantly higher bioluminescent s...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837150/ https://ncbi.nlm.nih.gov/pubmed/19219023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1930 |
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