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Cell-free production of Gaussia princeps luciferase – antibody fragment bioconjugates for ex vivo detection of tumor cells

Antibody fragments (scFvs) fused to luciferase reporter proteins have been used as highly sensitive optical imaging probes. Gaussia princeps luciferase (GLuc) is an attractive choice for a reporter protein because it is small and bright and does not require ATP to stimulate bioluminescence-producing...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Patel, Kedar G., Ng, Patrick P., Kuo, Chiung-Chi, Levy, Shoshana, Levy, Ronald, Swartz, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939902/
https://ncbi.nlm.nih.gov/pubmed/19852937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.10.087
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