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Evaluation of drug-induced tissue injury by measuring alanine aminotransferase (ALT) activity in silkworm hemolymph

BACKGROUND: Our previous studies suggest silkworms can be used as model animals instead of mammals in pharmacologic studies to develop novel therapeutic medicines. We examined the usefulness of the silkworm larvae Bombyx mori as an animal model for evaluating tissue injury induced by various cytotox...

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書誌詳細
主要な著者: Inagaki, Yoshinori, Matsumoto, Yasuhiko, Kataoka, Keiko, Matsuhashi, Naoya, Sekimizu, Kazuhisa
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545979/
https://ncbi.nlm.nih.gov/pubmed/23137391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-13-13
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