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Evaluation of drug-induced tissue injury by measuring alanine aminotransferase (ALT) activity in silkworm hemolymph

BACKGROUND: Our previous studies suggest silkworms can be used as model animals instead of mammals in pharmacologic studies to develop novel therapeutic medicines. We examined the usefulness of the silkworm larvae Bombyx mori as an animal model for evaluating tissue injury induced by various cytotox...

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Hlavní autoři: Inagaki, Yoshinori, Matsumoto, Yasuhiko, Kataoka, Keiko, Matsuhashi, Naoya, Sekimizu, Kazuhisa
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545979/
https://ncbi.nlm.nih.gov/pubmed/23137391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-13-13
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