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Fluorescence imaging for a noninvasive in vivo toxicity-test using a transgenic silkworm expressing green fluorescent protein

In drug development, the toxicity of candidate chemicals must be carefully examined in an animal model. Here we developed a live imaging technique using silkworms for a noninvasive toxicity test applicable for drug screening. Injection of carbon tetrachloride, a tissue-injuring chemical, into transg...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Inagaki, Yoshinori, Matsumoto, Yasuhiko, Ishii, Masaki, Uchino, Keiro, Sezutsu, Hideki, Sekimizu, Kazuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462092/
https://ncbi.nlm.nih.gov/pubmed/26061948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11180
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