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Enhancing solubility of deoxyxylulose phosphate pathway enzymes for microbial isoprenoid production

BACKGROUND: Recombinant proteins are routinely overexpressed in metabolic engineering. It is well known that some over-expressed heterologous recombinant enzymes are insoluble with little or no enzymatic activity. This study examined the solubility of over-expressed homologous enzymes of the deoxyxy...

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書目詳細資料
Main Authors: Zhou, Kang, Zou, Ruiyang, Stephanopoulos, Gregory, Too, Heng-Phon
格式: Artigo
語言:Inglês
出版: BioMed Central 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545872/
https://ncbi.nlm.nih.gov/pubmed/23148661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-148
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